Open AccessDifferential Infectivity and Division ofToxoplasma gondiiin Human Peripheral Blood Leukocytes
Author(s) -
Jacqueline Y. Chan,
Rosanne Séguin,
Lloyd H. Kasper
Publication year - 2000
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.68.8.4822-4826.2000
Subject(s) - biology , toxoplasma gondii , infectivity , peripheral blood , cell division , in vitro , permissive , virology , immunology , monocyte , microbiology and biotechnology , cell , antibody , virus , genetics
When tachyzoites were incubated with human peripheral blood leukocytes in vitro, more monocytes and dendritic cells than neutrophils or lymphocytes were infected. Although tachyzoites were able to divide in each of these cell types, monocytes and dendritic cells were more permissive to rapid tachyzoite division than neutrophils or lymphocytes.