Open AccessInteraction of Enteropathogenic or Enterohemorrhagic Escherichia coli with HeLa Cells Results in Translocation of Cortactin to the Bacterial Adherence Site
Author(s) -
Vlademir Vicente Cantarelli,
Akira Takahashi,
Yukihiro Akeda,
Kenichi Nagayama,
Takeshi Honda
Publication year - 2000
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.68.1.382-386.2000
Subject(s) - enteropathogenic escherichia coli , shigella flexneri , biology , escherichia coli , microbiology and biotechnology , hela , cortactin , shigella , enterobacteriaceae , virology , cell , gene , biochemistry , cytoskeleton
Infection of cultured HeLa epithelial cells with enteropathogenicEscherichia coli (EPEC) or enterohemorrhagicE. coli (EHEC) O157:H7 results in accumulation of cortactin under the adherent bacteria. Tyrosine phosphorylation of cortactin is not induced following HeLa cell infection with EHEC or EPEC, contrary to what has been reported to occur withShigella flexneri.