Open AccessChlamydia psittaci -Infected Dendritic Cells Communicate with NK Cells via Exosomes To Activate Antibacterial Immunity
Author(s) -
Nadine Radomski,
Axel Karger,
Kati Franzke,
Elisabeth Liebler–Tenorio,
Rico Jahnke,
Svea Matthiesen,
Michael R. Knittler
Publication year - 2019
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.00541-19
Subject(s) - biology , chlamydia psittaci , microvesicles , interleukin 12 , secretion , proinflammatory cytokine , innate immune system , interferon , microbiology and biotechnology , exosome , immunology , interferon gamma , immune system , chlamydia , inflammation , cytotoxic t cell , microrna , in vitro , biochemistry , gene
Dendritic cells (DCs) and natural killer (NK) cells are critically involved in the early response against various bacterial microbes. Functional activation of infected DCs and NK cell-mediated gamma interferon (IFN-γ) secretion essentially contribute to the protective immunity againstChlamydia . How DCs and NK cells cooperate during the antichlamydial response is not fully understood.
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