Mosquito Bite-Induced Controlled Human Malaria Infection with Plasmodium vivax or P. falciparum Generates Immune Responses to Homologous and Heterologous Preerythrocytic and Erythrocytic Antigens
Author(s) -
C. E. Hall,
Lisa M. Hagan,
Elke S. BergmannLeitner,
Donna Tosh,
Jason W. Bennett,
Jason A. Regules,
Ilin Chuang,
Evelina Angov,
Sheetij Dutta,
Debasish Chattopadhyay,
Anjali Yadava
Publication year - 2018
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.00541-18
Subject(s) - biology , malaria , virology , plasmodium falciparum , plasmodium vivax , heterologous , antigen , immunology , antibody , immune system , circumsporozoite protein , homologous chromosome , malaria vaccine , genetics , gene
Seroepidemiological studies on the prevalence of antibodies to malaria antigens are primarily conducted on individuals from regions of endemicity. It is therefore difficult to accurately correlate the antibody responses to the timing and number of prior malaria infections.
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