Open AccessIsolation of Protein-Associated Circular DNA from Healthy Cattle Serum
Author(s) -
Mathis Funk,
Karin Gunst,
Vincent Lučanský,
Hermann Müller,
Harald zur Hausen,
Ethel Michele De Villiers
Publication year - 2014
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.00846-14
Subject(s) - biology , bovine spongiform encephalopathy , isolation (microbiology) , dna , virology , circular dna , genetics , prion protein , microbiology and biotechnology , gene , medicine , genome , disease
Three replication-competent single-stranded DNA molecules sharing nucleotide similarity to transmissible spongiform encephalopathy (TSE)-associated isolate Sphinx 2.36 were isolated from healthy bovine serum.