Open AccessKinetoplast DNA Network: Evolution of an Improbable Structure
Author(s) -
Julius Lukeš,
D. Lys Guilbride,
Jan Votýpka,
Alena Zı́ková,
Rob Benne,
Paul T. Englund
Publication year - 2002
Publication title -
eukaryotic cell
Language(s) - English
Resource type - Journals
eISSN - 1535-9778
pISSN - 1535-9786
DOI - 10.1128/ec.1.4.495-502.2002
Subject(s) - kinetoplast , biology , mitochondrial dna , circular dna , dna , kinetoplastida , genetics , microbiology and biotechnology , genome , gene , protozoal disease , malaria , immunology
Kinetoplast DNA (kDNA) is the most structurally complex mitochondrial DNA in nature. Unique to the single mitochondrion of unicellular flagellates of the order Kinetoplastida, kDNA is best known as a giant network of thousands of catenated circular DNAs (an electron micrograph of a network is shown
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