Mitochondrial Genomic Dysfunction Causes Dephosphorylation of Sch9 in the Yeast Saccharomyces cerevisiae | Zendy

Shigeyuki Kawai | Zendy; Jörg Urban | Zendy; Manuele Piccolis | Zendy; Nicolas Panchaud | Zendy; Claudio De Virgilio | Zendy; Robbie Loewith | Zendy

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Mitochondrial Genomic Dysfunction Causes Dephosphorylation of Sch9 in the Yeast Saccharomyces cerevisiae

Author(s) -

Shigeyuki Kawai,

Jörg Urban,

Manuele Piccolis,

Nicolas Panchaud,

Claudio De Virgilio,

Robbie Loewith

Publication year - 2011

Publication title -

eukaryotic cell

Language(s) - English

Resource type - Journals

eISSN - 1535-9778

pISSN - 1535-9786

DOI - 10.1128/ec.05157-11

Subject(s) - saccharomyces cerevisiae , protonophore , biology , dephosphorylation , phosphorylation , yeast , microbiology and biotechnology , mitochondrion , mutant , signal transduction , biochemistry , gene , phosphatase

TORC1-dependent phosphorylation of Saccharomyces cerevisiae Sch9 was dramatically reduced upon exposure to a protonophore or in respiration-incompetent ρ(0) cells but not in respiration-incompetent pet mutants, providing important insight into the molecular mechanisms governing interorganellar signaling in general and retrograde signaling in particular.

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