Uncoupling of the Patterns of Chromatin Association of Different Transcription Elongation Factors by a Histone H3 Mutant in Saccharomyces cerevisiae
Author(s) -
Amanda Lloyd,
Katie Pratt,
Erica A. Siebrasse,
Matthew D. Moran,
Andrea A. Duina
Publication year - 2008
Publication title -
eukaryotic cell
Language(s) - English
Resource type - Journals
eISSN - 1535-9778
pISSN - 1535-9786
DOI - 10.1128/ec.00348-08
Subject(s) - saccharomyces cerevisiae , biology , chromatin , histone , genetics , transcription (linguistics) , mutant , histone h3 , gene , microbiology and biotechnology , linguistics , philosophy
The transcription elongation complexes yFACT, Spt4/Spt5, and Spt6/Iws1 were previously shown to follow similar patterns of association across transcribed genes in Saccharomyces cerevisiae. Using a histone H3 mutant, we now provide evidence that the mechanism of association of yFACT across genes is separable from that adopted by Spt4/Spt5 and Spt6/Iws1.
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