Open AccessUltrasensitive Human Immunodeficiency Virus Type 1 p24 Antigen Assay Modified for Use on Dried Whole-Blood Spots as a Reliable, Affordable Test for Infant Diagnosis
Author(s) -
Janet C. Patton,
Gayle Sherman,
Ashraf Coovadia,
Wendy Stevens,
Tammy Meyers
Publication year - 2006
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.13.1.152-155.2006
Subject(s) - dried blood , spots , human immunodeficiency virus (hiv) , filter paper , virology , antigen , virus , whole blood , severe combined immunodeficiency , screening test , medicine , chromatography , immunology , biology , chemistry , pediatrics , pathology , microbiology and biotechnology , in vivo
The ultrasensitive human immunodeficiency virus (HIV) p24 antigen assay was modified for use on pediatric dried whole-blood spots on Whatman no. 1 filter paper. The modified assay was found to be reliable and accurate, making it an affordable tool for pediatric HIV diagnosis in developing countries.