Open AccessFalse-Negative Hepatitis B Virus (HBV) Surface Antigen in a Vaccinated Dialysis Patient with a High Level of HBV DNA in the United States
Author(s) -
Matthew C. Foy,
Chloe L. Thio,
Hyon S. Hwang,
Melissa Saulynas,
James P. Hamilton,
Derek M. Fine,
Mohamed G. Atta
Publication year - 2012
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.05696-11
Subject(s) - hbsag , virology , hepatitis b virus , medicine , antibody , hepatitis b , antigen , immunology , virus
Screening with hepatitis B surface antigen (HBsAg) is highly recommended for at-risk individuals. Mutations in the HBsAg can result in an inability to detect the virus during routine screening. We describe a hemodialysis patient found to have high levels of hepatitis B virus (HBV) DNA and HBV antibody but negative HBsAg on two routine assays.
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