Persistence of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant
Author(s) -
Wilbur H. Chen,
Lisa A. Jackson,
Kathryn M. Edwards,
Wendy A. Keitel,
Heather Hill,
Diana L. Noah,
C. Buddy Creech,
Shital M. Patel,
Brian Mangal,
Karen L. Kotloff
Publication year - 2015
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00475-15
Subject(s) - adjuvant , immunogenicity , vaccination , influenza a virus subtype h5n1 , virology , medicine , live attenuated influenza vaccine , influenza vaccine , pandemic , virus , immunology , antibody , covid-19 , disease , infectious disease (medical specialty)
The adjuvant AS03 is stockpiled for future formulations with new and existing vaccines for the control of pandemic influenza virus. We previously reported the immunogenicity of an A/H5N1 vaccine extemporaneously mixed with the AS03 adjuvant for 42 days following vaccination. This report extends those findings to 1 year after vaccination.
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