Evaluation of a Novel Enzyme-Linked Immunosorbent Assay To Detect Immunoglobulin G Antibody to Enolase for Serodiagnosis of Invasive Candidiasis | Zendy

Ana Laín | Zendy; Marı́a D. Moragues | Zendy; Juan Carlos GarcíaRuiz | Zendy; Joaquín Mendoza | Zendy; Ana Camacho | Zendy; Amalia del Palacio | Zendy; José Pontón | Zendy

Open Access

Evaluation of a Novel Enzyme-Linked Immunosorbent Assay To Detect Immunoglobulin G Antibody to Enolase for Serodiagnosis of Invasive Candidiasis

Author(s) -

Ana Laín,

Marı́a D. Moragues,

Juan Carlos GarcíaRuiz,

Joaquín Mendoza,

Ana Camacho,

Amalia del Palacio,

José Pontón

Publication year - 2007

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00396-06

Subject(s) - enolase , antibody , candida albicans , invasive candidiasis , recombinant dna , immunoglobulin g , immunology , biology , microbiology and biotechnology , medicine , biochemistry , immunohistochemistry , antifungal , fluconazole , gene

The performance of a new test to detect antibodies to Candida albicans recombinant enolase was investigated in 47 immunocompromised and 51 immunocompetent patients. The sensitivity, specificity, and positive and negative predictive values of the test for the diagnosis of invasive candidiasis were 81.0, 83.9, 79.1, and 85.5%, respectively.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research