Establishment of Reference Values of CD4 and CD8 Lymphocyte Subsets in Healthy Nigerian Adults
Author(s) -
D. K. Oladepo,
E.O. Idigbe,
RA Audu,
U. S. Inyang,
Godwin Imade,
Anne Philip,
Godfrey Okafor,
David O. Olaleye,
S. B. Mohammed,
N N Odunukwe,
T. Harry,
M. Edyong-Ekpa,
John Idoko,
AZ Musa,
Adebayo Lawrence Adedeji,
Abdulsalami Nasidi,
Y. Ya’aba,
K Ibrahim
Publication year - 2009
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00378-08
Subject(s) - lymphocyte subsets , human immunodeficiency virus (hiv) , cd8 , immunology , reference range , reference values , biology , lymphocyte , environmental health , demography , medicine , immune system , endocrinology , sociology
A total of 2,570 apparently healthy human immunodeficiency virus-negative adults from the six geopolitical zones in the country were enrolled in our study in 2006. The samples were assayed using the Cyflow technique. Data were analyzed using the Statistical Package for Social Scientists (SPSS). The majority (64%) of the participants had CD4 counts within the range of 501 to 1,000 cells/microl. The reference range for CD4 was 365 to 1,571 cells/microl, while the reference range for CD8 was 145 to 884 cells/microl.
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