Galactoxylomannan Does Not Exhibit Cross-Reactivity in the PlateliaAspergillusEnzyme Immunoassay | Zendy

Magdia De Jesus | Zendy; Emily Hackett | Zendy; Michelle Durkin | Zendy; Patricia Connolly | Zendy; Arturo Casadevall | Zendy; Rūta Petraitienė | Zendy; Thomas J. Walsh | Zendy; L. Joseph Wheat | Zendy

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Galactoxylomannan Does Not Exhibit Cross-Reactivity in the PlateliaAspergillusEnzyme Immunoassay

Author(s) -

Magdia De Jesus,

Emily Hackett,

Michelle Durkin,

Patricia Connolly,

Arturo Casadevall,

Rūta Petraitienė,

Thomas J. Walsh,

L. Joseph Wheat

Publication year - 2007

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00368-06

Subject(s) - immunoassay , cryptococcus neoformans , microbiology and biotechnology , aspergillus , enzyme , cryptococcosis , cross reactivity , cryptococcus , yeast , cross reactions , antibody , biology , chemistry , biochemistry , immunology

Given the recent report of a false-positive result in the Platelia Aspergillus enzyme immunoassay in a patient with cryptococcosis and in yeast extracts and purified galactoxylomannan of Cryptococcus neoformans, we evaluated culture extracts, purified polysaccharides, clinical specimens, and specimens from animals following experimental infection. Our results revealed no cross-reactions.

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