Open AccessAcute HIV-1 Seroconversion with an Unusual Plasma Biomarker Profile
Author(s) -
Najib Aziz,
Roger Detels,
Otoniel Martı́nez-Maza,
John Oishi,
Beth D. Jamieson,
Mallory D. Witt,
Anthony W. Butch
Publication year - 2013
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00366-13
Subject(s) - seroconversion , biomarker , human immunodeficiency virus (hiv) , antibody , viral load , virology , immunology , cytokine , medicine , chemistry , biochemistry
An unusual case of acute primary HIV-1 infection in a man with a high plasma viral load, a 51-fold increase in C-reactive protein, and antibodies against only gp160 is described. Numerous serum cytokine concentrations were elevated during HIV-1 seroconversion.
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