Pediatric Antibody Response to Community-Acquired Staphylococcus aureus Infection Is Directed to Panton-Valentine Leukocidin | Zendy

Eric L. Brown | Zendy; M. Gabriela Bowden | Zendy; Rebecca S. Bryson | Zendy; Kristina G. Hultén | Zendy; Andrea S. Bordt | Zendy; Andrea Forbes | Zendy; Sheldon L. Kaplan | Zendy

Open Access

Pediatric Antibody Response to Community-Acquired Staphylococcus aureus Infection Is Directed to Panton-Valentine Leukocidin

Author(s) -

Eric L. Brown,

M. Gabriela Bowden,

Rebecca S. Bryson,

Kristina G. Hultén,

Andrea S. Bordt,

Andrea Forbes,

Sheldon L. Kaplan

Publication year - 2008

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00360-08

Subject(s) - panton–valentine leukocidin , staphylococcus aureus , leukocidin , antibody , microbiology and biotechnology , immunoglobulin g , staphylococcal infections , medicine , immunology , methicillin resistant staphylococcus aureus , biology , virology , bacteria , genetics

We examined the antibody responses of pediatric patients infected with community-associated Staphylococcus aureus isolates. The data show that patients infected with Panton-Valentine leukocidin (PVL)-positive strains developed a dominant immunoglobulin G anti-PVL antibody response that correlates with markers of inflammation.

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