Demonstrated Efficacy of a Pilot Heterologous Whole-Spore Vaccine against Microsporidial Gill Disease in Rainbow Trout | Zendy

Jennifer E. Harkness | Zendy; Nicole Guselle | Zendy; David J. Speare | Zendy

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Demonstrated Efficacy of a Pilot Heterologous Whole-Spore Vaccine against Microsporidial Gill Disease in Rainbow Trout

Author(s) -

Jennifer E. Harkness,

Nicole Guselle,

David J. Speare

Publication year - 2013

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00340-13

Subject(s) - rainbow trout , heterologous , biology , microbiology and biotechnology , virology , fishery , zoology , fish <actinopterygii> , biochemistry , gene

Intraperitoneal vaccines using whole viable spores of the microsporidian Glugea anomala or Glugea hertwigi reduced the numbers of branchial xenomas by 80% and 91%, respectively, after a standard experimental infection of juvenile rainbow trout with the microsporidian Loma salmonae. Similar significant results were obtained when killed-spore preparations were used.

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