Antibody Responses in Mice Stimulated by Various Doses of the Potato-Derived Major Surface Antigen of Hepatitis B Virus | Zendy

Jung Won Youm | Zendy; Young Suk Won | Zendy; Jae Heung Jeon | Zendy; Ki Beom Moon | Zendy; Hyoung Chin Kim | Zendy; KeeSun Shin | Zendy; Hyouk Joung | Zendy; Hyun Soon Kim | Zendy

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Antibody Responses in Mice Stimulated by Various Doses of the Potato-Derived Major Surface Antigen of Hepatitis B Virus

Author(s) -

Jung Won Youm,

Young Suk Won,

Jae Heung Jeon,

Ki Beom Moon,

Hyoung Chin Kim,

KeeSun Shin,

Hyouk Joung,

Hyun Soon Kim

Publication year - 2010

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00262-10

Subject(s) - hbsag , antibody , antigen , virology , immunology , hepatitis b virus , virus , booster (rocketry) , medicine , biology , physics , astronomy

The ability of potato-derived major surface antigen of hepatitis B virus (P-HBsAg) to elicit antibody responses to different dosages of P-HBsAg ranging from 0.02 to 30 μg administered orally in mice was examined. All immunized groups produced specific serum IgG and fecal IgA antibodies against P-HBsAg, even at low levels (<5 μg), after administration of a 0.5-μg yeast-derived HBsAg (Y-HBsAg; LG Life Sciences, Republic of Korea) booster.

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