Serological Protection Induced by Haemophilus influenzae Type b Conjugate Vaccine in Mexican Children: Is a Booster Dose of the Vaccine Needed? | Zendy

Romeo S Rodrı́guez | Zendy; César Mascareñas | Zendy; Carlos J. CondeGlez | Zendy; Jaime Inostroza | Zendy; Sonia Villanueva | Zendy; María Elena Velázquez | Zendy; Miguel Ángel Sánchez-Alemán | Zendy; Gabriela Echániz-Avilés | Zendy

Open Access

Serological Protection Induced by Haemophilus influenzae Type b Conjugate Vaccine in Mexican Children: Is a Booster Dose of the Vaccine Needed?

Author(s) -

Romeo S Rodrı́guez,

César Mascareñas,

Carlos J. CondeGlez,

Jaime Inostroza,

Sonia Villanueva,

María Elena Velázquez,

Miguel Ángel Sánchez-Alemán,

Gabriela Echániz-Avilés

Publication year - 2010

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00249-10

Subject(s) - seroprevalence , conjugate vaccine , hib vaccine , medicine , serology , antibody , haemophilus influenzae , booster dose , virology , conjugate , pediatrics , immunization , immunology , microbiology and biotechnology , biology , antibiotics , mathematical analysis , mathematics

We determined the seroprevalence of protective antibodies against Hib in Mexican children under the age of five using a standardized enzyme-linked immunosorbent assay. Hib antibodies (≥ 0.15 μg/ml) were present in 95.34% (±1.14% [seroprevalence ± standard error]) of samples. Fewer children aged 30 to 47 months had protective Hib antibody levels (91.45% ± 2.60%) than children from 12 to 29 and 48 to 59 months (97.3% ± 1.34% and 97.44% ± 1.80%, respectively).

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