Evaluation of Antibodies against Different Epstein-Barr Virus Nuclear Antigen 1 Peptides in Diagnosis of Nasopharyngeal Carcinoma | Zendy

Ai-Di Gu | Zendy; Hao-Yuan Mo | Zendy; JinXin Bei | Zendy; Yan-Bo Xie | Zendy; Li-Zhen Chen | Zendy; Qi-Sheng Feng | Zendy; Tiebang Kang | Zendy; Yi-Xin Zeng | Zendy

Open Access

Evaluation of Antibodies against Different Epstein-Barr Virus Nuclear Antigen 1 Peptides in Diagnosis of Nasopharyngeal Carcinoma

Author(s) -

Ai-Di Gu,

Hao-Yuan Mo,

JinXin Bei,

Yan-Bo Xie,

Li-Zhen Chen,

Qi-Sheng Feng,

Tiebang Kang,

Yi-Xin Zeng

Publication year - 2009

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00207-08

Subject(s) - nasopharyngeal carcinoma , antibody , antigen , serology , virus , virology , epstein–barr virus , biology , immunology , medicine , radiation therapy

Epstein-Barr virus nuclear antigen 1 (EBNA1) is a protein expressed consistently in nasopharyngeal carcinoma (NPC). Although antibody levels against three different EBNA1 peptides were all high in NPC patients, the correlation between any two biomarkers was low. Therefore, the selection of distinct EBNA1 peptides could render different results in serological detection for individuals with NPC.

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