Use of Sera from Humans and Dolphins with Lacaziosis and Sera from Experimentally Infected Mice for Western Blot Analyses of Lacazia loboi Antigens | Zendy

Leonel Mendoza | Zendy; Andréa F. F. Belone | Zendy; Raquel Vilela | Zendy; Manuela Rehtanz | Zendy; Gregory D. Bossart | Zendy; John S. Reif | Zendy; Patricia A. Fair | Zendy; Wendy Noke Durden | Zendy; Judy St. Leger | Zendy; Luiz R. Travassos | Zendy; Patrícia Sammarco Rosa | Zendy

Open Access

Use of Sera from Humans and Dolphins with Lacaziosis and Sera from Experimentally Infected Mice for Western Blot Analyses of Lacazia loboi Antigens

Author(s) -

Leonel Mendoza,

Andréa F. F. Belone,

Raquel Vilela,

Manuela Rehtanz,

Gregory D. Bossart,

John S. Reif,

Patricia A. Fair,

Wendy Noke Durden,

Judy St. Leger,

Luiz R. Travassos,

Patrícia Sammarco Rosa

Publication year - 2007

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00201-07

Subject(s) - paracoccidioides brasiliensis , paracoccidioidomycosis , antigen , biology , antibody , microbiology and biotechnology , virology , western blot , immunology , biochemistry , gene

Antibodies in the sera of patients with lacaziosis recognized an approximately 193-kDa antigen and other Lacazia loboi antigens. Paracoccidioides brasiliensis gp43 antigen was detected by all evaluated sera, but they failed to detect a protein with the same molecular mass in L. loboi extracts. This study is the first to examine the humoral response to L. loboi antigens by using multiple host sera.

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