Follow-Up Study of Tuberculosis-Exposed Supermarket Customers with Negative Tuberculin Skin Test Results in Association with Positive Gamma Interferon Release Assay Results
Author(s) -
Willeke P. J. Franken,
Ben F. P. J. Koster,
Ailko Bossink,
Steven Thijsen,
John J. M. Bouwman,
Jaap T. van Dissel,
Sandra M. Arend
Publication year - 2007
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00185-07
Subject(s) - tuberculin , skin test , interferon gamma , medicine , tuberculosis , tuberculin test , interferon γ , immunology , interferon gamma release assay , association (psychology) , mycobacterium tuberculosis , latent tuberculosis , pathology , cytokine , psychology , psychotherapist
We report a follow-up study of 29 subjects with negative tuberculin skin test (TST) results in association with positive gamma interferon release assay (IGRA) results, mainly due to responses to CFP-10 in the T-SPOT.TB assay, during a contact investigation. One year later, 12/29 subjects (41%) had converted to positive TST results in association with negative IGRA results.
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