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Cell-Mediated Immune Responses to Smallpox Vaccination
Author(s) -
SungHan Kim,
SangGu Yeo,
JaeHyun Cho,
Hong Bin Kim,
Nam Joong Kim,
Myoungdon Oh,
Kang Won Choe,
Youngmee Jee,
Haewol Cho
Publication year - 2006
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00181-06
Subject(s) - vaccinia , smallpox vaccine , vaccination , virology , smallpox , immune system , virus , immunology , variola virus , poxviridae , biology , orthopoxvirus , medicine , recombinant dna , biochemistry , gene
We report that vaccine dilution (1:1 or 1:10) and previous vaccinia virus vaccination status had no significant effect on cell-mediated immune responses (i.e., the immediate vaccinia virus-specific gamma interferon-producing T-cell response measured by enzyme-linked immunospot assay) 1 month after smallpox vaccination (Lancy-Vaxina; Berna Biotech, Switzerland).

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