Evaluation of the IMMY ALPHA Histoplasma Antigen Enzyme Immunoassay for Diagnosis of Histoplasmosis Marked by Antigenuria | Zendy

Ann M. LeMonte | Zendy; Lindsey Egan | Zendy; Patricia Connolly | Zendy; Michelle Durkin | Zendy; L. Joseph Wheat | Zendy

Open Access

Evaluation of the IMMY ALPHA Histoplasma Antigen Enzyme Immunoassay for Diagnosis of Histoplasmosis Marked by Antigenuria

Author(s) -

Ann M. LeMonte,

Lindsey Egan,

Patricia Connolly,

Michelle Durkin,

L. Joseph Wheat

Publication year - 2007

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00035-07

Subject(s) - histoplasmosis , immunoassay , histoplasma , antigen , enzyme , virology , alpha (finance) , immunology , histoplasma capsulatum , microbiology and biotechnology , medicine , chemistry , antibody , biology , biochemistry , cronbach's alpha , clinical psychology , psychometrics

The sensitivity of detection of antigenuria in patients positive by the MiraVista Diagnostics Histoplasma enzyme immunoassay (MVD EIA) was 44% with the IMMY ALPHA Histoplasma antigen EIA. The specificity was 84% with the IMMY EIA versus 98% with the MVD EIA. The correlation between assays for positive cases was weak (r(2) = 0.430).

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