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In Vitro Assessment of Antiborrelial Activity of OspA Vaccine Sera
Author(s) -
Paul T. Fawcett,
Carlos D. Rosé,
Kathleen M. Gibney
Publication year - 2002
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cdli.9.4.919-920.2002
Subject(s) - microculture , lyme disease , virology , in vitro , recombinant dna , biology , medicine , immunology , biochemistry , gene
Prevention of Lyme disease by the recombinant OspA-based vaccine reportedly works by preventing transmission of spirochetes from ticks to humans. We report on an in vitro microculture assay, which can be used to provide an indicator of the need for booster doses of vaccine.

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