Performance of Two Commercial Enzyme-Linked Immunosorbent Assay Kits Using Recombinant Glycoprotein G2 Antigen for Detection of Herpes Simplex Virus Type 2 Specific Antibodies
Author(s) -
Sharmila Reddy,
Pachamuthu Balakrishnan,
Uma Shanmugasundaram,
Sadras Panchatcharam Thyagarajan,
Suniti Solomon
Publication year - 2005
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cdli.12.2.359-360.2005
Subject(s) - virology , herpes simplex virus , recombinant dna , antibody , antigen , glycoprotein , enzyme , specific antibody , virus , biology , microbiology and biotechnology , immunology , biochemistry , gene
For 93 stored serum samples tested by HerpeSelect2 and the Euroimmun enzyme-linked immunosorbent assay for detection of herpes simplex virus type 2-specific immunoglobulin G antibodies, the concordance of positive and negative results was 100%. Moreover, all the results that were equivocal by HerpeSelect2 (negative by Euroimmun) were confirmed as being negative by a Western blot assay.
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