Open AccessAge-Specific Immune Response to HspA in Helicobacter pylori -Positive Persons in Mexico
Author(s) -
Peter P. Eamrad,
Javier Torres,
Onofre Muñoz,
Guillermo I. PérezPérez
Publication year - 2004
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cdli.11.5.983-985.2004
Subject(s) - helicobacter pylori , immune system , helicobacter infections , immunology , biology , medicine , microbiology and biotechnology , genetics
The immune response to heat shock protein A (HspA) in Helicobacter pylori-positive adults increases with age in developed countries. This response has not been studied with children or in developing countries (G. I. Pérez-Pérez, J. M. Thiberge, A. Labigne, and M. J. Blaser, J. Infect. Dis. 174:1046-1050, 1996). As determined by using a specific enzyme-linked immunosorbent assay, HspA seropositivity among 592 individuals in Mexico was <10% in children and increased to >40% in adults.
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