Open AccessKinetics of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibodies in 271 Laboratory-Confirmed Cases of SARS
Author(s) -
Zhongping He,
Qingming Dong,
Hui Zhuang,
Shujing Song,
Guoai Peng,
Guangxiang Luo,
Dominic E. Dwyer
Publication year - 2004
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cdli.11.4.792-794.2004
Subject(s) - severe acute respiratory syndrome , covid-19 , coronavirus , virology , severe acute respiratory syndrome coronavirus , respiratory system , antibody , medicine , specific antibody , betacoronavirus , sars virus , immunology , outbreak , infectious disease (medical specialty) , disease
The sensitivities and specificities of an immunofluorescence assay and an enzyme immunoassay for detection of antibodies specific for severe acute respiratory syndrome coronavirus (SARS-CoV) were compared for 148 laboratory-confirmed SARS cases. The appearance and persistence of SARS-CoV-specific antibodies were assessed, with immunoglobulin G detected in 59% of samples collected within 14 days and persisting for 60 to 95 days after the onset of illness.
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