Open AccessTranscriptional Analysis of Genes Encoding Shiga Toxin 2 and Its Variants in Escherichia coli
Author(s) -
Wenlan Zhang,
Martina Bielaszewska,
Alexander W. Friedrich,
Thorsten Kuczius,
Helge Karch
Publication year - 2005
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.71.1.558-561.2005
Subject(s) - shiga toxin , escherichia coli , stx2 , biology , shiga like toxin , microbiology and biotechnology , gene , enterobacteriaceae , toxin , genetics
Six of 37 non-O157 Escherichia coli strains possessing Shiga toxin (Stx) 2 gene variant stx(2d) or stx(2e) secreted no detectable Stx. These isolates produced significantly less stx mRNA than Stx2d, Stx2e, Stx2c, or Stx2 secretors did. Standard screening procedures miss a significant subset of E. coli harboring stx(2) variants.