Biogenesis of some antibiotics in the presence of 2-chloroethylphosphonic acid
Author(s) -
Arun Sharma,
S. R. PadwalDesai
Publication year - 1986
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.52.4.605-606.1986
Subject(s) - penicillium citrinum , streptomyces aureofaciens , streptomyces griseus , microbiology and biotechnology , antibiotics , fungus , food science , chemistry , biology , bacteria , biogenesis , microorganism , bacterial growth , biochemistry , botany , streptomyces , genetics , gene
2-Chloroethylphosphonic acid (CEPA) affected both the growth of and antibiotic production in Streptomyces aureofaciens, S. griseus, S. antibioticus, and Penicillium citrinum. Streptomyces strains seemed to be more sensitive to the presence of CEPA in the medium than did the fungus. A decrease in both growth and antibiotic production was observed with a concomitant increase in the concentration of the ethylene-releasing compound in the medium. Higher concentrations of CEPA completely inhibited the growth of the above microorganisms.
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