HupW Protease Specifically Required for Processing of the Catalytic Subunit of the Uptake Hydrogenase in the Cyanobacterium Nostoc sp. Strain PCC 7120 | Zendy

Pia Lindberg | Zendy; Ellenor Devine | Zendy; Karin Stensjö | Zendy; Peter Lindblad | Zendy

Open Access

HupW Protease Specifically Required for Processing of the Catalytic Subunit of the Uptake Hydrogenase in the Cyanobacterium Nostoc sp. Strain PCC 7120

Author(s) -

Pia Lindberg,

Ellenor Devine,

Karin Stensjö,

Peter Lindblad

Publication year - 2011

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.05957-11

Subject(s) - hydrogenase , protein subunit , protease , mutant , strain (injury) , biochemistry , nostoc , cyanobacteria , biology , enzyme , chemistry , microbiology and biotechnology , bacteria , gene , genetics , anatomy

The maturation process of [NiFe] hydrogenases includes a proteolytic cleavage of the large subunit. We constructed a mutant of Nostoc strain PCC 7120 in which hupW, encoding a putative hydrogenase-specific protease, is inactivated. Our results indicate that the protein product of hupW selectively cleaves the uptake hydrogenase in this cyanobacterium.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research