Bifunctional Gene Cluster lnqBCDEF Mediates Bacteriocin Production and Immunity with Differential Genetic Requirements | Zendy

Shun Iwatani | Zendy; Yuko Horikiri | Zendy; Takeshi Zendo | Zendy; Jiro Nakayama | Zendy; Kenji Sonomoto | Zendy

Open Access

Bifunctional Gene Cluster lnqBCDEF Mediates Bacteriocin Production and Immunity with Differential Genetic Requirements

Author(s) -

Shun Iwatani,

Yuko Horikiri,

Takeshi Zendo,

Jiro Nakayama,

Kenji Sonomoto

Publication year - 2013

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.03783-12

Subject(s) - bacteriocin , immunity , gene cluster , biology , gene , bifunctional , genetics , computational biology , cluster (spacecraft) , immune system , bacteria , biochemistry , computer science , catalysis , programming language

A comprehensive gene disruption of lacticin Q biosynthetic cluster lnqQBCDEF was carried out. The results demonstrated the necessity of the complete set of lnqQBCDEF for lacticin Q production, whereas immunity was flexible, with LnqEF (ABC transporter) being essential for and LnqBCD partially contributing to immunity.

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