Open AccessSelection of Bifidobacteria Based on Adhesion and Anti-Inflammatory Capacity In Vitro for Amelioration of Murine Colitis
Author(s) -
Julia Preising,
David Philippe,
Marita Gleinser,
Hua Wei,
Stéphanie Blum,
Bernhard J. Eikmanns,
Jan-Hendrik Niess,
Christian U. Riedel
Publication year - 2010
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.03127-09
Subject(s) - bifidobacterium bifidum , colitis , in vivo , in vitro , microbiology and biotechnology , adhesion , bifidobacterium , inflammatory bowel disease , strain (injury) , biology , immunology , bacteria , chemistry , medicine , lactobacillus , biochemistry , pathology , genetics , disease , organic chemistry , anatomy
Adhesion and anti-inflammatory properties of eight strains of bifidobacteria were tested using the intestinal epithelial cell lines Caco-2, T84, and HT29. Two strains were selected for further assessment of their anti-inflammatory capacity in two murine models of colitis.In vivo results confirmed the high anti-inflammatory capacity of aBifidobacterium bifidum strain.