Open AccessScreening for Antimicrobial Resistance Genes and Virulence Factors via Genome Sequencing
Author(s) -
Mads Bennedsen,
Birgitte StuerLauridsen,
Morten Danielsen,
Eric Johansen
Publication year - 2011
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02493-10
Subject(s) - virulence , gene , biology , genome , genetics , antibiotic resistance , in silico , virulence factor , dna sequencing , whole genome sequencing , computational biology , microbiology and biotechnology , bacteria
Second-generation genome sequencing and alignment of the resulting reads toin silico genomes containing antimicrobial resistance and virulence factor genes were used to screen for undesirable genes in 28 strains which could be used in human nutrition. No virulence factor genes were detected, while several isolates contained antimicrobial resistance genes.