Open AccessIdentification of a Polyketide Synthase Coding Sequence Specific for Anatoxin-a-Producing Oscillatoria Cyanobacteria
Author(s) -
Sabrina Cadel-Six,
Isabelle Iteman,
Caroline Peyraud-Thomas,
Stéphane Mann,
Olivier Ploux,
Annick Méjean
Publication year - 2009
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02478-08
Subject(s) - polyketide synthase , cyanobacteria , axenic , oscillatoria , biology , genome , geosmin , whole genome sequencing , genetics , strain (injury) , identification (biology) , polyketide , microbiology and biotechnology , computational biology , gene , botany , biosynthesis , bacteria , odor , anatomy , neuroscience
We report the identification of a sequence from the genome ofOscillatoria sp. strain PCC 6506 coding for a polyketide synthase. Using 50 axenic cyanobacteria, we found this sequence only in the genomes ofOscillatoria strains producing anatoxin-a or homoanatoxin-a, indicating its likely involvement in the biosynthesis of these toxins.