Identification of a Polyketide Synthase Coding Sequence Specific for Anatoxin-a-Producing Oscillatoria Cyanobacteria | Zendy

Sabrina Cadel-Six | Zendy; Isabelle Iteman | Zendy; Caroline Peyraud-Thomas | Zendy; Stéphane Mann | Zendy; Olivier Ploux | Zendy; Annick Méjean | Zendy

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Identification of a Polyketide Synthase Coding Sequence Specific for Anatoxin-a-Producing Oscillatoria Cyanobacteria

Author(s) -

Sabrina Cadel-Six,

Isabelle Iteman,

Caroline Peyraud-Thomas,

Stéphane Mann,

Olivier Ploux,

Annick Méjean

Publication year - 2009

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.02478-08

Subject(s) - polyketide synthase , cyanobacteria , axenic , oscillatoria , biology , genome , geosmin , whole genome sequencing , genetics , strain (injury) , identification (biology) , polyketide , microbiology and biotechnology , computational biology , gene , botany , biosynthesis , bacteria , odor , anatomy , neuroscience

We report the identification of a sequence from the genome ofOscillatoria sp. strain PCC 6506 coding for a polyketide synthase. Using 50 axenic cyanobacteria, we found this sequence only in the genomes ofOscillatoria strains producing anatoxin-a or homoanatoxin-a, indicating its likely involvement in the biosynthesis of these toxins.

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