Anti-Listeria Activities of Galleria mellonella Hemolymph Proteins
Author(s) -
Krishnendu Mukherjee,
Mobarak Abu Mraheil,
Silke Silva,
Daniela Müller,
Franz Cemič,
Jürgen Hemberger,
Torsten Hain,
Andreas Vilcinskas,
Trinad Chakraborty
Publication year - 2011
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02435-10
Subject(s) - galleria mellonella , hemolymph , listeria monocytogenes , microbiology and biotechnology , listeria , biology , bacteria , virulence , biochemistry , genetics , gene
We report the use of antimicrobial hemolymph proteins from the model host Galleria mellonella as an inhibitor for various Listeria strains, providing a novel source for antilisterial therapeutics. We also have shown that specific virulence-associated genes known to mediate antimicrobial resistance of Listeria in mammalian models indicated a similar function in Galleria.
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