Single-Cell and Population Lag Times as a Function of Cell Age
Author(s) -
Carmen Pin,
József Baranyi
Publication year - 2008
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02402-07
Subject(s) - generation time , lag , lag time , population , doubling time , time lag , escherichia coli , biology , phase lag , inoculation , cell , biological system , mathematics , computer science , genetics , medicine , immunology , computer network , environmental health , gene
After inoculation, the times to the first divisions are longer and more widely distributed for those Escherichia coli single cells that spent more time in the stationary phase prior to inoculation. The second generation times are still longer than the typical generation times in the exponential phase, and this extended the apparent lag time of the cell population. The greater the variability of the single-cell interdivision intervals, the shorter are both the lag time and the doubling time of the population.
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