Open AccessAdaptation to an Amoeba Host Leads to Pseudomonas aeruginosa Isolates with Attenuated Virulence
Author(s) -
Wai Leong,
Wee Han Poh,
Jonathan Williams,
Carla Lutz,
Masuma Hoque,
Yan Hong Poh,
Benny Yeo Ken Yee,
Cliff Chua,
Michael Givskov,
Martina L. Sanderson-Smith,
Scott A. Rice,
Diane McDougald
Publication year - 2022
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02322-21
Subject(s) - biology , virulence , pseudomonas aeruginosa , microbiology and biotechnology , protozoa , pathogen , bacteria , acanthamoeba , gene , genetics
Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute infections in plants and animals, including humans, and chronic infections in immunocompromised and cystic fibrosis patients. This bacterium is commonly found in soils and water, where bacteria are constantly under threat of being consumed by bacterial predators, e.g., protozoa.