Induction of a State of Iron Limitation in Uropathogenic Escherichia coli CFT073 by Cranberry-Derived Proanthocyanidins as Revealed by Microarray Analysis
Author(s) -
Gabriela Hidalgo,
André Ponton,
Julien Fatisson,
C O'May,
Bahareh Asadishad,
Tim Schinner,
Nathalie Tufenkji
Publication year - 2010
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02201-10
Subject(s) - escherichia coli , proanthocyanidin , bacteria , microbiology and biotechnology , chemistry , biology , biochemistry , food science , gene , genetics , polyphenol , antioxidant
Transcriptional profiles of uropathogenic Escherichia coli CFT073 exposed to cranberry-derived proanthocyanidins (PACs) were determined. Our results indicate that bacteria grown on media supplemented with PACs were iron deprived. To our knowledge, this is the first time that PACs have been shown to induce a state of iron limitation in this bacterium.
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