Probing 3-Hydroxyflavone for In Vitro Glycorandomization of Flavonols by YjiC | Zendy

Ramesh Prasad Pandey | Zendy; Prakash Parajuli | Zendy; Niranjan Koirala | Zendy; Je Won Park | Zendy; Jae Kyung Sohng | Zendy

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Probing 3-Hydroxyflavone for In Vitro Glycorandomization of Flavonols by YjiC

Author(s) -

Ramesh Prasad Pandey,

Prakash Parajuli,

Niranjan Koirala,

Je Won Park,

Jae Kyung Sohng

Publication year - 2013

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.02057-13

Subject(s) - flavonols , myricetin , kaempferol , fisetin , quercetin , chemistry , in vitro , isorhamnetin , biochemistry , antioxidant

The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-d/l-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.

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