Implications of Mobile Genetic Elements for Salmonella enterica Single-Nucleotide Polymorphism Subtyping and Source Tracking Investigations | Zendy

Shaoting Li | Zendy; Shaokang Zhang | Zendy; Leen Baert | Zendy; Balamurugan Jagadeesan | Zendy; Catherine NgomBru | Zendy; Taylor Griswold | Zendy; Lee S. Katz | Zendy; Heather A. Carleton | Zendy; Xiangyu Deng | Zendy

Open Access

Implications of Mobile Genetic Elements for Salmonella enterica Single-Nucleotide Polymorphism Subtyping and Source Tracking Investigations

Author(s) -

Shaoting Li,

Shaokang Zhang,

Leen Baert,

Balamurugan Jagadeesan,

Catherine NgomBru,

Taylor Griswold,

Lee S. Katz,

Heather A. Carleton,

Xiangyu Deng

Publication year - 2019

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.01985-19

Subject(s) - subtyping , salmonella enterica , biology , genetics , mobile genetic elements , single nucleotide polymorphism , plasmid , snp array , snp , genome , computational biology , salmonella , gene , genotype , bacteria , computer science , programming language

Despite increasingly routine use of WGS and SNP subtyping in outbreak and source tracking investigations, whether and how MGEs affect SNP subtyping has not been thoroughly investigated. Besides chromosomal MGEs, plasmids are frequently entangled in draft genome assemblies and yet to be assessed for their impact on SNP subtyping. This study provides evidence-based guidance on the treatment of MGEs in SNP analysis forSalmonella to infer phylogenetic relationship and SNP distance between isolates.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research