Open AccesscsrA Inhibits the Formation of Biofilms by Vibrio vulnificus
Author(s) -
Melissa K. Jones,
Elizabeth B. Warner,
James D. Oliver
Publication year - 2008
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.01810-08
Subject(s) - vibrio vulnificus , biofilm , microbiology and biotechnology , complementation , biology , pathogen , bacteria , genetics , gene , mutant
PCR screening of the shellfish-borne pathogenVibrio vulnificus revealedcsrA -negative strains, and these strains formed increased biofilm compared tocsrA -positive strains. Complementation intrans withcsrA resulted in reduced biofilm formation, similar to that bycsrA + strains. Our results provide evidence thatcsrA inhibits biofilm formation inV. vulnificus .