The Probiotic Escherichia coli Nissle 1917 Reduces Pathogen Invasion and Modulates Cytokine Expression in Caco-2 Cells Infected with Crohn's Disease-Associated E. coli LF82 | Zendy

Claudia Hüebner | Zendy; Yaoyao Ding | Zendy; Ivonne Petermann | Zendy; Christoph Knapp | Zendy; Lynnette R. Ferguson | Zendy

Open Access

The Probiotic Escherichia coli Nissle 1917 Reduces Pathogen Invasion and Modulates Cytokine Expression in Caco-2 Cells Infected with Crohn's Disease-Associated E. coli LF82

Author(s) -

Claudia Hüebner,

Yaoyao Ding,

Ivonne Petermann,

Christoph Knapp,

Lynnette R. Ferguson

Publication year - 2011

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.01601-10

Subject(s) - escherichia coli , microbiology and biotechnology , probiotic , biology , pathogen , crohn's disease , enterobacteriaceae , bacteria , cytokine , escherichia , disease , immunology , gene , medicine , biochemistry , genetics , pathology

Increased numbers of adherent invasive Escherichia coli (AIEC) have been found in Crohn's disease (CD) patients. In this report, we investigate the potential of the probiotic Escherichia coli Nissle 1917 (EcN) to reduce features associated with AIEC pathogenicity in an already established infection with AIEC reference strain LF82.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research