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Fluorescence in situ hybridization and real-time PCR analysis targeting the 16S rRNA gene of Akkermansia muciniphila were performed to determine its presence in the human intestinal tract. These techniques revealed that an A. muciniphila-like bacterium is a common member of the human intestinal tract and that its colonization starts in early life and develops within a year to a level close to that observed in adults (10(8) cells/g) but decreases (P &lt; 0.05) in the elderly.

applied and environmental microbiology

Intestinal Integrity and <i>Akkermansia muciniphila</i> , a Mucin-Degrading Member of the Intestinal Microbiota Present in Infants, Adults, and the Elderly

Intestinal Integrity and Akkermansia muciniphila , a Mucin-Degrading Member of the Intestinal Microbiota Present in Infants, Adults, and the Elderly