The VirAB-VirSR-AnrAB Multicomponent System Is Involved in Resistance of Listeria monocytogenes EGD-e to Cephalosporins, Bacitracin, Nisin, Benzalkonium Chloride, and Ethidium Bromide | Zendy

Xiaobing Jiang | Zendy; Yimin Geng | Zendy; Siyu Ren | Zendy; Tao Yu | Zendy; Yi Li | Zendy; Guosheng Liu | Zendy; Hailei Wang | Zendy; Hecheng Meng | Zendy; Lei Shi | Zendy

Open Access

The VirAB-VirSR-AnrAB Multicomponent System Is Involved in Resistance of Listeria monocytogenes EGD-e to Cephalosporins, Bacitracin, Nisin, Benzalkonium Chloride, and Ethidium Bromide

Author(s) -

Xiaobing Jiang,

Yimin Geng,

Siyu Ren,

Tao Yu,

Yi Li,

Guosheng Liu,

Hailei Wang,

Hecheng Meng,

Lei Shi

Publication year - 2019

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.01470-19

Subject(s) - microbiology and biotechnology , ethidium bromide , bacitracin , listeria monocytogenes , kanamycin , atp binding cassette transporter , nisin , biology , benzalkonium chloride , tetracycline , antibiotic resistance , antimicrobial , chemistry , bacteria , antibiotics , biochemistry , gene , genetics , chromatography , transporter , dna

This report describes TCS/ABC transporter modules characterized inListeria monocytogenes EGD-e. The modules consist of the VirSR TCS and the VirAB and AnrAB ABC transporters. Our results showed that this system is involved in nisin and bacitracin resistance, as well as resistance to cephalosporins, ethidium bromide (EtBr), and benzalkonium chloride (BC). In this system, VirAB is responsible only for antimicrobial sensing and signaling by VirSR, while AnrAB contributes to transportation of antimicrobials. Interestingly, VirAB itself, rather than the VirAB-VirSR-AnrAB system as a whole, contributes to kanamycin and tetracycline resistance.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research