Phosphate Starvation Promotes Swarming Motility and Cytotoxicity of Pseudomonas aeruginosa | Zendy

Manjeet Bains | Zendy; Lucía Fernández | Zendy; Robert E. W. Hancock | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Phosphate Starvation Promotes Swarming Motility and Cytotoxicity of Pseudomonas aeruginosa

Author(s) -

Manjeet Bains,

Lucía Fernández,

Robert E. W. Hancock

Publication year - 2012

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.01015-12

Subject(s) - swarming motility , swarming (honey bee) , quorum sensing , pseudomonas aeruginosa , virulence , microbiology and biotechnology , motility , biology , cytotoxicity , chemotaxis , secretion , phosphate , pseudomonadaceae , toxin , bacteria , gene , biochemistry , in vitro , genetics , receptor

We investigated the transcriptional responses of Pseudomonas aeruginosa under phosphate-deficient (0.2 mM) conditions compared to phosphate sufficiency (1 mM). This elicited enormous transcriptional changes in genes related to phosphate acquisition, quorum sensing, chemotaxis, toxin secretion, and regulation. This dysregulation also led to increased virulence-associated phenotypes, including swarming motility and cytotoxicity.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research