Pseudomonas aeruginosa Bacteriophage PA1Ø Requires Type IV Pili for Infection and Shows Broad Bactericidal and Biofilm Removal Activities | Zendy

Shukho Kim | Zendy; Marzia Rahman | Zendy; Sung Yong Seol | Zendy; Sang Sun Yoon | Zendy; Jungmin Kim | Zendy

Open Access

Pseudomonas aeruginosa Bacteriophage PA1Ø Requires Type IV Pili for Infection and Shows Broad Bactericidal and Biofilm Removal Activities

Author(s) -

Shukho Kim,

Marzia Rahman,

Sung Yong Seol,

Sang Sun Yoon,

Jungmin Kim

Publication year - 2012

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.00648-12

Subject(s) - pseudomonas aeruginosa , microbiology and biotechnology , lytic cycle , biofilm , pilus , bacteriophage , staphylococcus aureus , bacteria , biology , virology , chemistry , escherichia coli , virus , biochemistry , genetics , gene

We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.

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