Open AccessFibrinogen Induces Biofilm Formation by Streptococcus suis and Enhances Its Antibiotic Resistance
Author(s) -
Laetitia Bonifait,
Louis Grig,
Daniel Grenier
Publication year - 2008
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.00558-08
Subject(s) - biofilm , streptococcus suis , microbiology and biotechnology , fibrinogen , penicillin , antibiotics , antibiotic resistance , chemistry , biology , bacteria , virulence , biochemistry , gene , genetics
In this study, we showed that supplementing the culture medium with fibrinogen induced biofilm formation by Streptococcus suis in a dose-dependent manner. Biofilm-grown S. suis cells were much more resistant to penicillin G than planktonic cells. S. suis bound fibrinogen to its surface, a property that likely contributes to biofilm formation.