Dioxygenation of the Biphenyl Dioxygenation Product | Zendy

Heike Overwin | Zendy; Myriam González | Zendy; Valentina Méndez | Zendy; Michael Seeger | Zendy; Victor Wray | Zendy; Bernd Höfer | Zendy

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Dioxygenation of the Biphenyl Dioxygenation Product

Author(s) -

Heike Overwin,

Myriam González,

Valentina Méndez,

Michael Seeger,

Victor Wray,

Bernd Höfer

Publication year - 2012

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.00492-12

Subject(s) - biphenyl , chemistry , metabolite , stereochemistry , catabolism , substrate (aquarium) , burkholderia , bacteria , biochemistry , biology , metabolism , organic chemistry , genetics , ecology

Two biphenyl dioxygenases (BphAs) were shown to catalyze dioxygenation of biphenyldienediol in the nonoxidized ring to form the respective symmetrical biphenyl-bis-dienediol. This novel metabolite served as a growth substrate for both BphA source strains. Its catabolism through the upper bph pathway of Burkholderia xenovorans LB400 was analyzed.

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