Absence of Serotype-Specific Surface Antigen in Laboratory Variants of Epidemic-Associated Listeria monocytogenes Strains | Zendy

Ying Cheng | Zendy; Lili Yue | Zendy; Driss Elhanafi | Zendy; Sophia Kathariou | Zendy

Open Access

Absence of Serotype-Specific Surface Antigen in Laboratory Variants of Epidemic-Associated Listeria monocytogenes Strains

Author(s) -

Ying Cheng,

Lili Yue,

Driss Elhanafi,

Sophia Kathariou

Publication year - 2007

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.00473-07

Subject(s) - serotype , listeria monocytogenes , biology , microbiology and biotechnology , virology , listeria , monoclonal antibody , antigen , antibody , genetics , bacteria

Variants that lacked reactivity with the serotype 4b-specific monoclonal antibody c74.22 and that lost susceptibility to certainListeria - or serotype 4b-specific phages were identified in the course of genetic studies with serotype 4bListeria monocytogenes strains H7550 and F2381L (epidemic clones I and II, respectively). Our findings suggest that such variants can become inadvertently established under laboratory conditions and suggest caution in work involving serotype 4b strains and genetic constructs thereof.

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